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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1143276ed97f6ebf32618239218f5f495c0b81ed3f6f4da74b718c975bb155d' 
  AND token = 'MpZer5LGpVYJp3d0H8N1t+GaamlHDgBuD3K2Z2tyFpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}