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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c99d5350c34b834c1774d0531a2bc35a5a7040f15b130ba7c1b6392f57a78ca' 
  AND token = 'xw6v+vSvpOQdZgbBukfhmVWHUWb1ie9mHdv1w1RoJYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}