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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a27bafb5fa155c89e627c3059fd64d8a56de929d77fd8926d854ba349ef7e45' 
  AND token = 'XRyz+oddmhiBjMfS9l5m/4anWWUq44WlyLyRwO2PkeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}