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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7542db3fc07db553554602a36fd1612a20aba7cb9f8edabda93e5d21d767c0e' 
  AND token = 'iPfJr8Amtb8gR6L8BWUUSDKO4EhQFsQqTTnTvHSq9Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}