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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143c6493058c1caefad02e9e3dadda7f2ada21ffad2269f66b8d14b61d6ad9f1' 
  AND token = 'NYEWRZuZVRPkL9xsxsu8ZjNJcHrauKzuH8eXVo2UX28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}