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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '146e412b514e76892cdbd74418cde8bf1d25bdd3246e4e9a080debfede6e1acf' 
  AND token = 'ckHptO3XVv/cNA/JWmda4Tz4u7QMl+tTV92j6ZWsBOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}