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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10ab3ec9c5db38a9c149d8ed497e7e21abd34bee6fb555fcc2324b7dcbce1d8f' 
  AND token = 'RKqcERjW8IZxeykRQF9BtvFheW3rsRw/Bk57WXDjyN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}