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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6aa67c872d525502d9bf3994783b32088df6ed8aa05e4738e215712b6bff8b7' 
  AND token = 'HaG0he2KQ+py4sfwKNKJqJhQ5KKnN8424iqjMBoE0aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}