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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '037ee42a3ebfd4f6350d8ad1a925a78a47388cb338a73988d70de0551993b5ac' 
  AND token = 'UxCgIMkbk7hkDToIVyF/3hLxGTfSrM5yLv3J3wxhlTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}