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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4044cbb6dd803eba9c3bec1c65cd43469ba5b42c16dd896cb3a4d82681b1265d' 
  AND token = 'lpcSzziMstLEIpwSR0p+CW1nmce+9xoG7RY4DDWEsKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}