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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c623059b9aa899455f97fc5c26e8534bec838f7f64ed044b7cae1475ff3605ec' 
  AND token = 'IaOekh/en/9CEqUFRLwDStCrlDwhdZkeGWNGwjAxKfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}