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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '318bebe687005896cc3f948a51ef20792b40170f1721dfeacab12c1aad2ac207' 
  AND token = '4zEEOep+rXb2Z9i95sYdNvsND3AMOzehnTbzRFMtfi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}