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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be78d3bd2239d0b59483a15022aaf532e8e52dcebc9ce2892db404dbfe581d1f' 
  AND token = 'S4R5V8xcO5OdkIurFcf1crat1As0pa8RRt57n0J8AH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}