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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c9d1c9daa22b8773eee89e4054ecf2a149babb43c8747a421c6e7824f205c58' 
  AND token = '522bXco/SRxB1SRxZLkcEtNPA31twvWhyaH7293dV4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}