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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38fda4e3dc2273190bd20fae1d466882356afe85fa5a7d56c7a9d5a0a76d7e4d' 
  AND token = '++CxI+VxRgBDUIdP2OjZr3UYgUPgE63x80t04Zkehs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}