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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81569d546b397f52642773fab6f97271c4e2a500dab6eb39a9d250ab23e61cc6' 
  AND token = 'kJxRDY+hlemywokW8fwFZ4Wz7PHuFcx35OIdHwWy14A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}