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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2a902daf778f004395e0549fc3904fb73090ea4f43c368604f1aa1795e9ab4b' 
  AND token = 'JV03fToRQgK7oM57XNhsT5x1MDMYuyEfZHApZoQ+8Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}