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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c9df7c7cb1877c7662155d0b8e5e09bd9b5fb8f90debc3568be4e484ff7ed78' 
  AND token = 'fMaR2/PY/wnfVIRueLeBmTflo6ktgM8VDcWdrvNilNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}