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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f20549d69e26e80f468ebf38dd3063156cf40767fb281f5b4810ac2a4d8a5a7' 
  AND token = 'oZTshEa1fzpVPnl8mfQ5qQZv5IT20KhD2jTmLcnrzrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}