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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129bc9c4d8eef84f6d5c04b7e628913b5a6fb60bfa9dde8f8f654dac4c7d0e0f' 
  AND token = 'dn4NDyO/Orfp4gVRAXQ/8te+cDElR23Lc0/NSemHQ5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}