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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a674ed1d832acf66d3977b06f144578751b79a76226ff0cf4af5ffc11e22757' 
  AND token = 'nB+GiOT7w7D23YB8x5yZYTPitp7gp5FlTMM4sk5PXII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}