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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9065e601d208512f65bcd18a7d74e6489c1780b244af51ce52048f4832ac4294' 
  AND token = 'aiS2Ub9TvZvauxZcV+Pot7m7TyAOv1Vc6Ec6+9GUmEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}