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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a14ba4a8a3024277e0ebcae5af3761d142eddd66b1c53c9fa213d051e04bf89e' 
  AND token = 'VLSEfkKpYHj4kIEJvuz5bjrk7LZQhD+7FLMyr3HnUmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}