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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48217ee225849fc133f6b49b88a77f82922c5bfb739bbb3f446704f8ab886707' 
  AND token = 'IYDSUekpsbvK4T1M2/j37QGA4JmIQVTNo2sQxnH2zKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}