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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '488d2ec96b4fce1d8f12cac6cac123874927fd2257810d6d295b8b20f4da887d' 
  AND token = 'Ua5NtUsminBPDvefo/5yNL/zDFIMDMTUcNTnYqSWlIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}