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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486668966f40dadde52e3361d3b3d3b43a27fa134ce4469c7433a9c12a3b4a77' 
  AND token = '89zxrqvRlerVgBrqQgQjBitBXNa0OkuBvTdZCMeTS4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}