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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3344aa6e8994503a6f550f798c0399d0c7a27815e695d098f4aac046c5e2154c' 
  AND token = 'B2EAW1DkP8ErsOGTV6WBLrMKxJWU/YpZFyfOOZN8Xz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}