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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343b9dea154540bf33759cfc9ede91aa45d9b2be794e57656d4009b5b9de98b8' 
  AND token = 'vROeqjeRczhO/GG4Ml6C1iD5MQ/PAsDlq4TKD4WIkwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}