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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '052126b6a434de16c6785cb28dc510b0819b1e50038373e1d0d7082910dc6f22' 
  AND token = 'AyqTzcBEb6PFyHJUJVSoLpNyjPfxbjJ1F79k5M1Q8ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}