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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489193ef228aff8aa3cc1665a3b157ad0bcedb822f0a13a55a4f59a4d6af47a0' 
  AND token = 'C6x+va7vrRJHoJeSe8eLAjzb24aMl2PpMy8gnFCgCXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}