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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8a22c069686dd7c3c0cd17e1764e80af61f202b31cf8ef88d21566c92eab17' 
  AND token = 'iyxd1emvGyCeTlSXJ15KWiBIqvDtSZ/m3WggTbdpPpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}