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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2186424d8920a29eda5c7d2ded3c81dbb55fc00f36b0bb093063b7be03b9a95a' 
  AND token = '2r4L/s9ZaTFzzcl9gxTBCLd7YU6S0njtMkjM2BOdRVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}