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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16005b04f578e0cb44a2f7c5391a940db1404a8d7f9b5936334669396245cf9d' 
  AND token = 'VocSSH1An8ND/3qWk0gPSnfSSFfvMdF4Tj7QC5/Ra/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}