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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44859688747b957dc21eb29cec47c7f25159c02966f38ca44ddb21a3c92c2898' 
  AND token = 'eqWZ4DJL5ICDc0F5TaoykH9iaMM6alPyjhZ8z8/dHy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}