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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f84b60e90de5826031a100f7cc28c75dc773e51f871d35b815466fb015f14cf0' 
  AND token = 'MXroUBr8HqGsi1HIZNcmJ5i1yYwItqRnJIHSLrl7XIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}