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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bb7a5a7c6076e479018d84df8bd2e6c19d8fcc6b1ebe0edeb55d930a3f20a57' 
  AND token = '8LeGqO432D34QGSLrHMuVVuf7P4PDE2hxVChbkN90Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}