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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f640c01c627fbf4f4b17a1d86bfc7f9811d78108803b57d927afd1ade3f5ae73' 
  AND token = 'BlK+R2T6NR65YjwMFPI7SRrKZ8yWMBPhaI6YV5mvnIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}