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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d6310601d82c155b32a72bd0f5f9aea6df32a825bd2df57f266d47945c96e15' 
  AND token = '7D8+keMDfyMLx6X5IMBwVeVN0mkr8cJxvJIE1M6V3fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}