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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0bb804a1d95687ffb93ad5c26f8adf27cf85108fb5db5f0b01023e356a0208b' 
  AND token = 'UAal2VZJXf1CV1iiM2xo7aTEm9XqocKtEfW1zCUB4eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}