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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cffd421ea803711e4f3ff016986976d3e77b9a6b65540e1bfe03e5aee84ffb6' 
  AND token = '9hss9u3xFbyvLs6Kx5lw46FK+ly6fVjP0qbfe1LzXYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}