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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '900f7c5951ebc7c3e65fb1f935a56fb1e743be47b52f268434566cf7493f155b' 
  AND token = '/gkPNmZUqFxKfQNQrmzI9YKUA7rXZKGqkwGb05iNHz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}