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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'beeacc215153224810d25378aab35848cddaf440d48ad31b9864bc626b3e2e94' 
  AND token = 'DfEAxAVTopWdLl/a6MN5sJPM8i7G7yGE0bZC+L0vJiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}