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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12c64d60dabf1a0d495d2b792063a41bc8b228af6f955fd4c0c4a03a8c6b465' 
  AND token = 'Q/VE++rox46irbeNY3QnQS45IxakpXPag2U4ez64Tno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}