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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a288b25080db88d787f93bd659ee9f6d00e112bb1e6c7b22fe105f4f2e0b4a47' 
  AND token = 'LTERKcHlHDBeMT7B0Sl+JMsOCXJYRqyRb9aB/OTJr9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}