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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d384a294fee3f054d78f0ea6102579a5bce8b4a4103f22210157582239676b0' 
  AND token = '9DKlou9l0iGi5Dz6aW/z1W9vjwHD5NiBiTovB+x24Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}