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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82e91141ff31f72c55254b797bbf9fa3f6e1a09245099db6e273c4e3aed63956' 
  AND token = 'RVPyTNRd/wv2sWLU0eN13z/vA25BIL7hXvPS0V38l9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}