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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00918079f87dab2b9a4c6ed316d34049363608a40fdd7196192d5457068c6b69' 
  AND token = 'QLZbV9Q4MDSfw6RV+rXUjI5WC81M+t7qsAtiGtAda4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}