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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ff10de7bd26a1559e54b32279fe63cc8832963ead8678ee167c760d89529894' 
  AND token = 'ftCeGhR+tKAuK4ZIocLMftlwPhGxLRVihi3TasX0Naw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}