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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b8293fb04b2a064e93ed952e34651485be45d1a5e7f3a3d87bdad54915c3a16' 
  AND token = '2uQjjFrLK0WcdNb9FlSYH5o2y1biz2Dsph4d7bXDqnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}