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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b38d1a01dee215ad228a31aeac7c7410aa7498d0cdd8bd226ce138751e533b5c' 
  AND token = 'm0026dwrv7htIHd04mIyYEFmxdvZn6KvYmxz4rzGJGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}